期刊
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
卷 25, 期 8, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/0960-1317/25/8/084010
关键词
dielectrophoresis; hydrophoresis; separation; filtration; integrated
类别
资金
- University of Wollongong-China Scholarship Council
- CSIRO Office of Chief Executive Top-up Scholarship
Microfluidic manipulation of biological objects from mixture has a significant application in sample preparation and clinical diagnosis. This work presents a dielectrophoresis-active hydrophoretic device for continuous label-free particle separation and filtration. This device comprises interdigitated electrodes and a hydrophoretic channel. According to the difference of lateral positions of polystyrene particles, the device can run at separation or filtration modes by altering the power supply voltages. With an applied voltage of 24 Vp-p, both 3 and 10 mu m beads had close lateral positions and were redirected to the same outlet. Under a voltage of 36 Vp-p, beads with the diameters of 3 and 10 mu m had different lateral positions and were collected from the different outlets. Separation of 5 and 10 mu m particles was achieved to demonstrate the relatively small size difference of the beads. This device has great potential in a range of lab-on-a-chip applications.
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