期刊
COMPUTATIONAL MECHANICS
卷 54, 期 4, 页码 911-919出版社
SPRINGER
DOI: 10.1007/s00466-013-0931-y
关键词
PVAD; Residence time; FSI; Isogeometric analysis; Biomechanics; FEM; Blood flow
资金
- Burroughs Wellcome Fund
- NSF [OCI-1150184, OCI-1055091]
A continuum-based model of particle residence time for moving-domain fluid mechanics and fluid-structure interaction (FSI) computations is proposed, analyzed, and applied to the simulation of an adult pulsatile ventricular assist device (PVAD). Residence time is a quantity of clinical interest for blood pumps because it correlates with thrombotic risk. The proposed technique may be easily implemented in any flow or FSI solver. In the context of PVADs the results of the model may be used to assess how efficiently the pump moves the blood through its interior. Three scalar measures of particle residence time are also proposed. These scalar quantities may be used in the PVAD design with the goal of reducing thrombotic risk.
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