期刊
COMPTES RENDUS CHIMIE
卷 17, 期 2, 页码 141-145出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crci.2012.11.017
关键词
Multicomponent reactions (MCRs); One-pot reaction; Hexahydroquinolines; Triton X-100; Non-ionic surfactant; Dimedone
资金
- Payame Noor University
A facile and efficient synthesis of hexahydroquinoline derivatives (5a-o) was reported via a four-component condensation reaction of aldehydes, dimedone, methyl aceto acetate and ammonium acetate in the presence of Triton X-100 in water at room temperature. The use of just 20 mol % of Triton X-100 in water solvent is sufficient. The FT-IR, F-19 NMR, H-1 NMR, C-13 NMR spectra and elemental analysis confirm the structure of the compounds. (c) 2012 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
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