4.7 Article

The use of human sewage screening for community surveillance of hepatitis E virus in the UK

期刊

JOURNAL OF MEDICAL VIROLOGY
卷 88, 期 5, 页码 915-918

出版社

WILEY
DOI: 10.1002/jmv.24403

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epidemiology; variation; detection

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资金

  1. Wellcome Trust
  2. BBSRC [BBS/E/D/20241864] Funding Source: UKRI
  3. Biotechnology and Biological Sciences Research Council [BBS/E/D/20241864] Funding Source: researchfish

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Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-infected hepatitis patients. J. Med. Virol. 88:915-918, 2016. (c) 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc.

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