期刊
JOURNAL OF MEDICAL ENTOMOLOGY
卷 52, 期 3, 页码 447-451出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/jme/tjv017
关键词
Aedes aegypti; Aedes albopictus; chikungunya; dengue; transmission
资金
- National Institutes of Health (NIH) [R21 A1073389]
- U.S. Army Medical Department's Long Term Healthcare Education and Training program
The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric distribution and shared mosquito vectors. Groups of Aedes aegypti (L.) and Aedes albopictus (Skuse) were orally infected with 1.5 x 10(5) PFU/ml of CHIKV and 3.2 x 10(6) FFU/ml of DENV-2 simultaneously or separately in inverse orders and evaluated for dissemination and transmission by qRT-PCR. Simultaneous dissemination of both viruses was detected for all groups in Ae. aegypti and Ae. albopictus while cotransmission of CHIKV and DENV-2 only occurred at low rates after sequential but not simultaneous infection.
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