期刊
COLLOIDS AND SURFACES B-BIOINTERFACES
卷 118, 期 -, 页码 243-248出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfb.2014.03.053
关键词
Hydroxyapatite; Vaterite; SERS; Silver nanoparticles; Calcium carbonate; Particles
资金
- Provincia autonoma di Trento
- Alexander von Humboldt-Stiftung
- RFBR [12-03-33088 mol_a_ved]
- Government of the Russian Federation [14.Z50.31.0004]
- Marie Curie project [PIRSES-GA-2013-612673]
An elegant route for hydroxyapatite (HA) particle synthesis via ionic exchange reaction is reported. Calcium carbonate particles (CaCO3) were recrystallized into HA beads in water solution with phosphate ions. The size of initial CaCO3 particles was controlled upon the synthesis by varying the amount of ethylene glycol (EG) in aqueous solution. The average size of HA beads ranged from 0.6 0.1 to +/- 4.3 +/- 1.1 mu m. Silver nanoparticles were deposited on the surface of HA and CaCO3 particles via silver mirror reaction. Surface enhanced Raman scattering of silver functionalized beads was demonstrated by detecting Rhodamine B. CaCO3 and HA particles have a great potential for design of carrier which can provide diagnostic and therapeutic functions. (C) 2014 Elsevier B.V. All rights reserved.
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