Synthesis of ZnO nanoparticles and evaluation of antioxidant and cytotoxic activity

ZnO nanoparticles were synthesized by thermal decomposition Method and were characterized by UV-vis spectroscopy, XRD, SEM, EDX and TEM analysis. The resultant nanoparticles are nearly spherical and size is in the range of 40-50 nm. The antioxidant behavior of ZnO nanoparticles was assessed by scavenging free radicals of 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) with varying nanoparticle concentration and time interval individually. The DPPH scavenging activity was monitored by UV-vis spectrophotometer. ZnO nanoparticles were also showing cytotoxic activity which was studied by hemolytic potentiality test. (C) 2013 Published by Elsevier B.V.