期刊
COLLOIDS AND SURFACES B-BIOINTERFACES
卷 88, 期 2, 页码 614-621出版社
ELSEVIER
DOI: 10.1016/j.colsurfb.2011.07.051
关键词
Carboxylated multi-walled carbon nanotube; Pyrocatechol violet; Chemically modified electrode; Uric acid; Xanthine; Hypoxanthine
资金
- Shandong Province Natural Science Foundation, China [Y2006B28]
A sensitive and selective electrochemical method was developed for simultaneous determination of uric acid (UA), xanthine (XA) and hypoxanthine (HX) based on a poly (pyrocatechol violet)/carboxyl functionalized multi-walled carbon nanotubes composite film modified electrode. The preparation and basic electrochemical performance of the novel composite film modified glassy carbon electrode were investigated in details. The electrochemical behaviors of UA, XA and HX at the modified electrode were studied by cyclic voltammetry. The results showed that this new electrochemical sensor exhibited excellent electrocatalytic activity towards the oxidation of the three analytes. The mechanism of catalysis was discussed. The anodic peaks of the three species were well defined with lowered oxidation potential and enhanced oxidation peak currents, so the modified electrode was used for simultaneous voltammetric measurement of UA, XA and HX by differential pulse voltammetry. Under the optimum conditions, the detection limits were 0.16 mu mol L-1 for UA, 0.05 mu mol L-1 for XA and 0.20 mu mol L-1 for HX, respectively (S/N of 3). The proposed method has been successfully applied to simultaneous determination of UA, XA and HX in human serum samples. (C) 2011 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据