期刊
COLLOID AND POLYMER SCIENCE
卷 291, 期 6, 页码 1375-1380出版社
SPRINGER
DOI: 10.1007/s00396-012-2868-7
关键词
Hydrogels; Magnetic nanoparticles; Organic-inorganic hybrids; Polysaccharides; Self-assembly
资金
- Ministry of Education, Culture, Sports, Science and Technology (MEXT) [20107011, 23107510, 2206]
- Grants-in-Aid for Scientific Research [23681021, 22107011] Funding Source: KAKEN
Novel organic-inorganic hybrid nanoparticles consisting of polymer-hydrogel nanoparticles (nanogels) and iron oxide were developed for potential biomedical applications. Hybrid nanoparticles were prepared by a simple procedure using polysaccharide nanogels as a reactive site for iron oxide formation. The hybrid nanoparticles have a narrow size distribution with a diameter of approximately 30 nm and show high colloidal stability. These nanohybrid particles could be used as a contrast medium for magnetic resonance imaging or for magnetic hyperthermia therapy.
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