A Complex Case of Neuro-Behcet's Disease in a Patient Previously Diagnosed with Multiple Sclerosis: A Case Report

Multiple sclerosis (MS) and Neuro-Behcet's disease (NBD) have been associated with a range of neuropsychiatric symptoms, including fatigue, cognitive impairment, depression, bipolar disorder, anxiety, sexual dysfunction, and other behavioral disturbances that are characterized by remissions and exacerbations at different points during the course of the disease. We present an interesting case of NBD in a 48-year-old female who had previously been diagnosed with MS. Exploration of this patient's various neuropsychiatric symptoms, their misattribution first to psychopathology and then subsequently to a variety of neurological problems exemplifies the potential pitfalls in diagnosis of a seemingly rare disorder. The role of psychosocial stress-related inflammatory changes in the patient's behavioral and neurological symptoms is explored as well as the potential psychological and medical effects of delayed diagnosis and treatment.