4.3 Article

Wnt Signaling Pathway in Schizophrenia

期刊

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
卷 13, 期 5, 页码 755-764

出版社

BENTHAM SCIENCE PUBL
DOI: 10.2174/1871527312666131223113521

关键词

Adenomatous polyposis coli; glycogen synthase kinase-3; schizophrenia; Wnt signaling pathway

资金

  1. National Natural Science Foundation of China [306770755, 81171266, 81271481]
  2. Shanghai Pujiang Program [10PJ1408800]
  3. Shanghai Scientific and Technological Innovation Project [11140900400]

向作者/读者索取更多资源

The Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better understanding of the Wnt pathway might contribute to developing new and more effective tools for diagnosis and treatment of schizophrenia.

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