期刊
CLINICS IN PERINATOLOGY
卷 39, 期 2, 页码 289-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.clp.2012.04.005
关键词
Congenital diaphragmatic hernia; Pulmonary hypoplasia; Pulmonary hypertension; Lung/head ratio; Liver herniation; EXIT procedure; Tracheal occlusion; Fetal breathing
资金
- NHLBI NIH HHS [K08 HL092062] Funding Source: Medline
Congenital diaphragmatic hernia (CDH) is a common birth anomaly. Absence or presence of liver herniation and determination of lung-to-head ratio are the most accurate predictors of prognosis for fetuses with CDH. Though open fetal CDH repair has been abandoned, fetal endoscopic balloon tracheal occlusion promotes lung growth in fetuses with severe CDH. Although significant improvements in lung function have not yet been shown in humans, reversible or dynamic tracheal occlusion is promising for select fetuses with severe CDH. This article reviews advances in prenatal diagnosis of CDH, the experimental basis for tracheal occlusion, and its translation into human clinical trials.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据