期刊
CLINICS IN LIVER DISEASE
卷 16, 期 4, 页码 717-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cld.2012.08.005
关键词
Alcoholic hepatitis; Aminotransferases; Maddrey's discriminant function; Liver biopsy; Steroids in alcoholic hepatitis; Enteral nutrition in alcoholic hepatitis; Pentoxifylline; Liver transplantation
Alcoholic hepatitis is a form of severe, cholestatic liver disease that results from consumption of large amount of alcohol during a sustained period of time in a subset of alcoholics. Symptoms could be mild and nonspecific to more severe. The diagnosis of alcoholic hepatitis can be made with a thorough history, physical examination, and review of laboratory results. Liver biopsy is confirmatory but generally not indicated for the diagnosis. Abstinence is the key form of therapeutic intervention. Despite variable results in clinical trials, corticosteroids and pentoxifylline seem to provide moderate survival benefit. Liver transplantation in acute alcoholic hepatitis is contentious.
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