期刊
CLINICS IN LIVER DISEASE
卷 15, 期 3, 页码 665-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cld.2011.05.004
关键词
Chronic hepatitis C virus; Peginterferon; Sustained virologic response; Protease inhibitors; Polymerase inhibitors; IL28B genotype
资金
- Conatus
- Exalenz
- Human Genome Sciences
- Roche/Genentech
- Romark
- Abbott
- Anadys
- Bristol-Myers Squibb
- Gilead
- Globeimmune
- Zymogenetics
Remarkable progress has been achieved in the treatment of chronic hepatitis C virus (HCV) since interferon was first used to treat this pathogen more than 20 years ago. This article reviews the mechanisms through which interferon is believed to suppress HCV and lead to SVR. These observations are used to speculate as to whether an all-oral antiviral cocktail could cure HCV in the near future.
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