期刊
CLINICS IN LIVER DISEASE
卷 13, 期 3, 页码 487-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cld.2009.05.012
关键词
Thrombopoietin; Thrombocytopenia; Cirrhosis; Hepatitis C; Interferon treatment; Thrombopoietin receptor agonists
Thrombocytopenia is a condition of unusually low level of platelets in blood, resulting from an imbalance between the production and destruction of platelets, and is associated with aplastic anemia, myelodysplasia, and idiopathic thrombocytopenic purpura (ITP). Thrombocytopenia can also be associated with severe chronic liver disease as a result of several factors that may act in concert, including reduced production of the endogenous thrombopoietic growth factor, thrombopoietin (TPO). This article examines the nature of thrombocytopenia, ITP, and TPO.
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