期刊
CLINICS IN LABORATORY MEDICINE
卷 29, 期 1, 页码 115-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cll.2009.01.007
关键词
Biomarker; Proteomics; Mass spectrometry; Discovery; Validation
资金
- Department of Defense [PC074313]
- Hillman Foundation
- David Scaife Foundation
A major goal of cancer research is elucidating the molecular events underlying carcinogenesis, with the goal of discovering better diagnostic markers and therapeutic targets. Proteomics aims to facilitate this process by applying newly developed methods and advanced analytic tools, such as mass spectrometry, for the investigation of the protein complement en masse. Proteomics is the comprehensive study of proteins and is aimed at analyzing their structure, function, modifications, expression, interactions, and localization in complex biological systems. This article reviews the state-of-the art in mass spectrometry-based approaches and their application for cancer biomarker discovery and validation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据