期刊
CLINICS IN CHEST MEDICINE
卷 35, 期 1, 页码 87-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccm.2013.09.012
关键词
Infection in COPD; Airway colonization; Chronic infection; New strain exacerbations; Pneumonia and COPD; Innate immunity in COPD; Virulence factors; Vicious-circle hypothesis
资金
- VA Merit Review
- NHLBI
This article represents a review of the current literature on the role of infection in the pathogenesis of chronic obstructive pulmonary disease (COPD), in stable disease, exacerbations, and pneumonia. It outlines the complex interactions between respiratory pathogens and host immune defenses that underlie the clinical manifestations of infection in COPD.
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