期刊
CLINICAL TOXICOLOGY
卷 50, 期 3, 页码 215-217出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/15563650.2012.660696
关键词
Metabolic; Perfusion; CNS; Psychological
类别
We report the case of a 39-year-old woman who presented with serotonin syndrome and hypoglycaemia likely due to intoxication with a very high dose of venlafaxine. This case of venlafaxine-associated hypoglycaemia was treated first by glucose perfusion, but despite large doses, hypoglycaemia recurred. Blood glucose normalized after injection of octreotide, eliminating the need for hypertonic glucose. Octreotide has been shown to decrease glucose requirements and the number of hypoglycaemic episodes in patients with sulfonylurea-induced hypoglycaemia but, to our knowledge, its ability to resolve hypoglycaemic episodes due to massive venlafaxine overdose has not yet been described.
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