相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function
Carla Garza-Lombo et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
The Gly(972)Arrg Variant of Human IRS1 Gene Is Associated with Variation in Glomerular Filtration Rate Likely Through Impaired Insulin Receptor Signaling
Farook Thameem et al.
DIABETES (2012)
Blood pressure influences end-stage renal disease of Cd151 knockout mice
Norman Sachs et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Hold tight or you'll fall off: CD151 helps podocytes stick in high-pressure situations
Ambra Pozzi et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Inhibition of MTOR Disrupts Autophagic Flux in Podocytes
Davide P. Cina et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)
The podocyte cytoskeleton-key to a functioning glomerulus in health and disease
Gavin I. Welsh et al.
NATURE REVIEWS NEPHROLOGY (2012)
Dysregulated Nephrin in Diabetic Nephropathy of Type 2 Diabetes: A Cross Sectional Study
Belinda Jim et al.
PLOS ONE (2012)
Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
Dudley W. Lamming et al.
SCIENCE (2012)
Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species
Eun Young Kim et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2012)
Receptor-isoform-selective insulin analogues give tissue-preferential effects
Sara G. Vienberg et al.
BIOCHEMICAL JOURNAL (2011)
Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle
Tetsuya Kubota et al.
CELL METABOLISM (2011)
Effects of Insulin and High Glucose on Mobilization of Slo1 BKCa Channels in Podocytes
Eun Young Kim et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
Markus Goedel et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
Ken Inoki et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
Saskia F. Heeringa et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression
Tobias B. Huber et al.
KIDNEY INTERNATIONAL (2011)
Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity
Akira Mima et al.
KIDNEY INTERNATIONAL (2011)
Acute Insulin Stimulation Induces Phosphorylation of the Na-Cl Cotransporter in Cultured Distal mpkDCT Cells and Mouse Kidney
Eisei Sohara et al.
PLOS ONE (2011)
Effect of Thiazolidinediones on Albuminuria and Proteinuria in Diabetes: A Meta-analysis
Pantelis A. Sarafidis et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2010)
Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function
Gavin I. Welsh et al.
CELL METABOLISM (2010)
Nephrin Is Expressed on the Surface of Insulin Vesicles and Facilitates Glucose-Stimulated Insulin Release
Alessia Fornoni et al.
DIABETES (2010)
Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes
Mervi E. Hyvonen et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis
Elizabeth J. Brown et al.
NATURE GENETICS (2010)
Regulatory Action on Rosiglitazone by the US Food and Drug Administration
Janet Woodcock et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice
Hongyu Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis
Youli Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential
Hiroyuki Mori et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Renal Function in Glycogen Storage Disease Type I, Natural Course, and Renopreservative Effects of ACE Inhibition
Danielle H. J. Martens et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Glomerular filtration barrier
Borje Haraldsson et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2009)
Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1
R. Lennon et al.
DIABETOLOGIA (2009)
Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease
Antonino Belfiore et al.
ENDOCRINE REVIEWS (2009)
Significance and Management of Proteinuria in Kidney Transplant Recipients
Hatem Amer et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease
Wilfred Lieberthal et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
The PPARγ Agonist Pioglitazone Ameliorates Aging-Related Progressive Renal Injury
Hai-Chun Yang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy
Rachel Lennon et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)
Rapamycin has dual opposing effects on proteinuric experimental nephropathies: is it a matter of podocyte damage?
Juan Torras et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)
Insulin signalling in the heart
Luc Bertrand et al.
CARDIOVASCULAR RESEARCH (2008)
The podocyte and diabetes mellitus: is the podocyte the key to the origins of diabetic nephropathy?
Gaddameedi R. Reddy et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2008)
It's not all about nephrin
M. Simons et al.
KIDNEY INTERNATIONAL (2008)
Insulin regulates SOCS2 expression and the mitogenic effect of IGF-1 in mesangial cells
Keiji Isshiki et al.
KIDNEY INTERNATIONAL (2008)
Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death
T. Tejada et al.
KIDNEY INTERNATIONAL (2008)
Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor
Swasti Tiwari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
mToR inhibitors-induced proteinuria: mechanisms, significance, and management
Emmanuel Letavernier et al.
Transplantation Reviews (2008)
Insulin increases the activity of mesangial BK channels through MAPK signaling
Ruth M. Foutz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells
Moin A. Saleem et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Association of VASP with TRPC4 in PKG-mediated inhibition of the store-operated calcium response in mesangial cells
Xiaoxia Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Skeletal muscle capillary responses to insulin are abnormal in late-stage diabetes and are restored by angiogensin-converting enzyme inhibition
Lucy H. Clerk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Central insulin regulates heart rate and arterial blood flow - An endothelial nitric oxide synthase-dependent mechanism altered during diabetes
Cendrine Cabou et al.
DIABETES (2007)
Insulin's impact on renal sodium transport and blood pressure in health, obesity, and diabetes
Swasti Tiwari et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
MAP kinase signalling pathways in cancer
A. S. Dhillon et al.
ONCOGENE (2007)
Nephrin is critical for the action of insulin on human glomerular podocytes
Richard J. M. Coward et al.
DIABETES (2007)
Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066E14Rik
Jaakko Patrakka et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
High sirolimus levels may induce focal segmental glomerulosclerosis de novo
Emmanuel Letavernier et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
The role of the IGF system in cancer growth and metastasis: Overview and recent insights
Amir Abbas Samani et al.
ENDOCRINE REVIEWS (2007)
Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin
Daniel G. Fuster et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Rapamycin prevents early steps of the development of diabetic nephropathy in rats
Yi Yang et al.
AMERICAN JOURNAL OF NEPHROLOGY (2007)
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible
Bernward Hinkes et al.
NATURE GENETICS (2006)
ERK MAP kinase in G1 cell cycle progression and cancer
Satoru Torii et al.
CANCER SCIENCE (2006)
Spectrum of renal diseases associated with extreme forms of insulin resistance
Carla Musso et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF
SC Satchell et al.
KIDNEY INTERNATIONAL (2006)
Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats
Nuria Lloberas et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Insulin increases gelatinase activity in rat glomerular mesangial cells via ERK- and PI-3 kinase-dependent signalling
MPS Lee et al.
DIABETES OBESITY & METABOLISM (2006)
Activation of vascular protein kinase C-β inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance
K Naruse et al.
DIABETES (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
Critical nodes in signalling pathways: insights into insulin action
CM Taniguchi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Reactive oxygen species-induced activation of the MAP kinase signaling pathways
James A. McCubrey et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Drug Insight: thiazolidinediones and diabetic nephropathy - relevance to renoprotection
U Panchapakesan et al.
NATURE CLINICAL PRACTICE NEPHROLOGY (2005)
The human glomerular podocyte is a novel target for insulin action
RJM Coward et al.
DIABETES (2005)
Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms
SS Shen et al.
MODERN PATHOLOGY (2005)
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
J Reiser et al.
NATURE GENETICS (2005)
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis
MP Winn et al.
SCIENCE (2005)
From the periphery of the glomerular capillary wall toward the center of disease - Podocyte injury comes of age in diabetic nephropathy
G Wolf et al.
DIABETES (2005)
IGF-I/insulin hybrid receptors in human endothelial cells
MD Nitert et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2005)
Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes
RT Watson et al.
ENDOCRINE REVIEWS (2004)
RNAi-based analysis of CAP, Cbl, and CrkII function in the regulation of GLUT4 by insulin
P Mitra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
From hyperglycemia to diabetic kidney disease: The role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines
BF Schrijvers et al.
ENDOCRINE REVIEWS (2004)
Clinical course of genetic diseases of the insulin receptor (Type A and Rabson-Mendenhall syndromes) - A 30-year prospective
C Musso et al.
MEDICINE (2004)
Insulinand its receptor: structure, function and evolution
P De Meyts
BIOESSAYS (2004)
Nonhepatic glucose production in humans
A Battezzati et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Different patterns of insulin resistance in relatives of type 1 diabetic patients with retinopathy or nephropathy
S Hadjadj et al.
DIABETES CARE (2004)
Global prevalence of diabetes - Estimates for the year 2000 and projections for 2030
S Wild et al.
DIABETES CARE (2004)
Insulin receptors and renal sodium handling in hypertensive fructose-fed rats
C Catena et al.
KIDNEY INTERNATIONAL (2003)
Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension
C Catena et al.
AMERICAN JOURNAL OF HYPERTENSION (2003)
CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility
JM Kim et al.
SCIENCE (2003)
Nephrin expression is reduced in human diabetic nephropathy - Evidence for a distinct role for glycated albumin and angiotensin II
S Doublier et al.
DIABETES (2003)
Evidence for a novel TGF-β1-independent mechanism of fibronectin production in mesangial cells overexpressing glucose transporters
C Weigert et al.
DIABETES (2003)
Nephrinuria in diabetic nephropathy of type 1 diabetes
A Patari et al.
DIABETES (2003)
Cell biology of the glomerular podocyte
H Pavenstadt et al.
PHYSIOLOGICAL REVIEWS (2003)
IRS proteins and the common path to diabetes
MF White
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Nephropathy in type I diabetes: A manifestation of insulin resistance and multiple genetic susceptibilities? Further evidence from the Pittsburgh Epidemiology of Diabetes Complication Study
TJ Orchard et al.
KIDNEY INTERNATIONAL (2002)
Insulin activates Na+/H+ exchanger 3:: biphasic response and glucocorticoid dependence
J Klisic et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)
Regulation of adhesive interaction between podocytes and glomerular basement membrane
M Kretzler
MICROSCOPY RESEARCH AND TECHNIQUE (2002)
Role of human liver, kidney, and skeletal muscle in postprandial glucose homeostasis
C Meyer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Prevalence of the metabolic syndrome among US adults - Findings from the Third National Health and Nutrition Examination Survey
ES Ford et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)
Insulin signalling and the regulation of glucose and lipid metabolism
AR Saltiel et al.
NATURE (2001)
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin
T Takano et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
DB Donoviel et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2
JM Cunnick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Peroxisome proliferator-activated receptor-γ agonist troglitazone protects against nondiabetic glomerulosclerosis in rats
LJ Ma et al.
KIDNEY INTERNATIONAL (2001)
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10
SH Chiang et al.
NATURE (2001)
Renal gluconeogenesis - Its importance in human glucose homeostasis
JE Gerich et al.
DIABETES CARE (2001)
Insulin-mediated increases in renal plasma flow are impaired in insulin-resistant normal subjects
JC ter Maaten et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2000)
Role of brain insulin receptor in control of body weight and reproduction
JC Brüning et al.
SCIENCE (2000)
CAP defines a second signalling pathway required for insulin-stimulated glucose transport
CA Baumann et al.
NATURE (2000)
Thiazolidinedione compounds ameliorate glomerular dysfunction independent of their insulin-sensitizing action in diabetic rats
K Isshiki et al.
DIABETES (2000)
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome
N Boute et al.
NATURE GENETICS (2000)
Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo A specific vascular action of insulin
K Kuboki et al.
CIRCULATION (2000)
Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis
JM Kaplan et al.
NATURE GENETICS (2000)
分享论文
