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Healthy aging and disease: role for telomere biology?

期刊

CLINICAL SCIENCE
卷 120, 期 9-10, 页码 427-440

出版社

PORTLAND PRESS LTD
DOI: 10.1042/CS20100385

关键词

aging; Alzheimer's disease; atherosclerosis; heart failure; longevity; Parkinson's disease; telomerase; telomere

资金

  1. Netherlands Heart Foundation [2006B140, 2006T003]
  2. Netherlands Organization for Scientific Research (NWO VENI) [916.76.170]
  3. Interuniversitair Cardiologisch Instituut Nederland (ICIN)
  4. National Heart, Lung, and Blood Institute [HL85817]

向作者/读者索取更多资源

Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease, Type 2 diabetes, neurological diseases and cancer. Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process.

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