期刊
CLINICAL RHEUMATOLOGY
卷 32, 期 2, 页码 161-165出版社
SPRINGER LONDON LTD
DOI: 10.1007/s10067-012-2041-1
关键词
Animal model; Induce; Rheumatoid arthritis
类别
资金
- National Natural Foundation of China [81000786]
- Shenzhen foundation [201103348]
At present, rheumatoid arthritis (RA) is considered a type of autoimmune disease. Its pathology is not certain, and effective drugs with less toxicity have not been established. The establishment and application of animal models are effective methods for RA research, especially using animal models similar to humans. Arthritis is more heterogeneous, and this is an important starting point when discussing animal models for arthritis. Animal models are instrumental in understanding the etiology and pathogenetic mechanisms of RA. Appropriate animal models should be selected according to experiments because they have different traits. Various methods have been applied to induce arthritis in animal experimental models, which have provided important insights into the etiopathogenetic mechanisms of human RA. This review was written to give a broad introduction of the current stage of RA model and hope to offer beneficial help for RA-related research.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据