期刊
CLINICAL RHEUMATOLOGY
卷 29, 期 1, 页码 91-93出版社
SPRINGER LONDON LTD
DOI: 10.1007/s10067-009-1272-2
关键词
Adalimumab; Beh sigma et disease; Pulmonary artery aneurysm; TNF-alpha inhibitor
类别
Beh sigma et's disease (BD) is a multisystem disorder characterized by vasculitis. Pulmonary vascular problems such as pulmonary artery aneurysms (PAA) are reported to indicate poor prognosis and high mortality. We describe a 43-year-old man who presented with life threatening bilateral PAA and thromboembolic disease due to BD. He was treated with prednisone and pulse cyclophosphamide and was poorly responsive to the conventional immunosuppression. The introduction of adalimumab therapy stabilized his PAA. We report that the inhibition of TNF-alpha using the neutralizing monoclonal antibody adalimumab has the potential to induce rapid, complete, and long-lasting remission in a life-threatening manifestation of BD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据