相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Concurrent Assessment of Hepatic and Intestinal Cytochrome P450 3A Activities Using Deuterated Alfentanil
E. D. Kharasch et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR
Antonia H. Tolson et al.
ADVANCED DRUG DELIVERY REVIEWS (2010)
Selection of Alternative CYP3A4 Probe Substrates for Clinical Drug Interaction Studies Using In Vitro Data and In Vivo Simulation
Robert S. Foti et al.
DRUG METABOLISM AND DISPOSITION (2010)
Using drug probes to monitor hepatic drug metabolism in critically ill patients: midazolam, a flawed but useful tool for clinical investigation of CYP3A activity?
Chris Kirwan et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2010)
Methadone Pharmacokinetics Are Independent of Cytochrome P4503A (CYP3A) Activity and Gastrointestinal Drug Transport Insights from Methadone Interactions with Ritonavir/Indinavir
Evan D. Kharasch et al.
ANESTHESIOLOGY (2009)
Towards a Quantitative Framework for the Prediction of DDIs Arising from Cytochrome P450 Induction
L. M. Almond et al.
CURRENT DRUG METABOLISM (2009)
Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity
Evan D. Kharasch et al.
DRUG AND ALCOHOL DEPENDENCE (2009)
In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective
Valeria Chu et al.
DRUG METABOLISM AND DISPOSITION (2009)
Up-regulation of P-glycoprotein by HIV Protease Inhibitors in a Human Brain Microvessel Endothelial Cell Line
Jason A. Zastre et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Pregnane X Receptor (PXR) Regulates P-Glycoprotein at the Blood-Brain Barrier: Functional Similarities between Pig and Human PXR
Melanie Ott et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Scientific and Regulatory Perspectives on Metabolizing Enzyme-Transporter Interplay and Its Role in Drug Interactions: Challenges in Predicting Drug Interactions
Lei Zhang et al.
MOLECULAR PHARMACEUTICS (2009)
Assessment of Blood-Brain Barrier Permeability Using the In Situ Mouse Brain Perfusion Technique
Rong Zhao et al.
PHARMACEUTICAL RESEARCH (2009)
Cytochrome P450 Induction by Rifampicin in Healthy Subjects: Determination Using the Karolinska Cocktail and the Endogenous CYP3A4 Marker 4β-Hydroxycholesterol
K. P. Kanebratt et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)
Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: The role of complex biophase distribution kinetics
Dorien Groenendaal et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Limitations of using a single postdose midazolam concentration to predict CYP3A-mediated drug interactions
Scott R. Penzak et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Quantitative correlations among CYP3A sensitive substrates and inhibitors: Literature analysis
Isabelle Ragueneau-Majlessi et al.
CURRENT DRUG METABOLISM (2007)
Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam
E. D. Kharasch et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
Pharmacokinetics and pharmacodynamics of alfentanil in P-glycoprotein-competent and P-glycoprotein-deficient mice: P-glycoprotein efflux alters alfentanil brain disposition and antinociception
J. Cory Kalvass et al.
DRUG METABOLISM AND DISPOSITION (2007)
The time to move cytochrome P450 induction into mainstream pharmacology is long overdue
Dennis A. Smith et al.
DRUG METABOLISM AND DISPOSITION (2007)
Drugs as CYP3A probes, inducers, and inhibitors
Yi-Tong Liu et al.
DRUG METABOLISM REVIEWS (2007)
In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation
Bjorn Bauer et al.
MOLECULAR PHARMACOLOGY (2006)
Limited sampling models for oral midazolam: Midazolam plasma concentrations, not the ratio of 1-hydroxymidazolam to midazolam plasma concentrations, accurately predicts AUC as a biomarker of CYP3A activity
LS Lee et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2006)
CYP induction-mediated drug interactions: in vitro assessment and clinical implications
Jiunn H. Lin
PHARMACEUTICAL RESEARCH (2006)
Single-point sampling for assessment of constitutive, induced, and inhibited cytochrome P450 3A activity with alfentanil or midazolam
HN Chaobal et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity
ED Kharasch et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Drug therapy - Drug metabolism and variability among patients in drug response
GR Wilkinson
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: Noninvasive assessment by use of pupillary miosis
ED Kharasch et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity
JC Gorski et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2003)
The conduct of in vitro and in vivo drug-drug interaction studies: A Pharmaceutical Research and Manufacturers of America (PhRMA) perspective
TD Bjornsson et al.
DRUG METABOLISM AND DISPOSITION (2003)
Disposition and miotic effects of oral alfentanil: A potential noninvasive probe for first-pass cytochrome P4503A activity
ED Kharasch et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2003)
Single plasma concentrations of 1′-hydroxymidazolam or the ratio of 1′-hydroxymidazolam:midazolam do not predict midazolam clearance in healthy subjects
JF Rogers et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2002)
Interaction of morphine, fentanyl, sufentanil, affientanil, and loperamide with the efflux drug transporter p-glycoprotein
C Wandel et al.
ANESTHESIOLOGY (2002)
In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration
YS Lin et al.
PHARMACOGENETICS (2001)
Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes
DS Streetman et al.
PHARMACOGENETICS (2000)
分享论文
