4.6 Article

A Comprehensive Approach to Identifying and Authenticating Botanical Products

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CLINICAL PHARMACOLOGY & THERAPEUTICS
卷 87, 期 2, 页码 175-186

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WILEY
DOI: 10.1038/clpt.2009.287

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  1. FDA HHS [5U01FD002071-09, 1U01FD003871-011] Funding Source: Medline

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Whether they are being taken as dietary supplements by the general public or being evaluated in a clinical study, the authenticity of botanical products is a matter of paramount concern. Botanical specimens and the dietary supplements derived from them can vary in quality and in chemical constituent profiles because of a number of factors. Subtle variations in botanical specimens are known to have profound effects on the quality, efficacy, and safety of botanical dietary supplements and can potentially alter the results of clinical studies that rely on these materials. A complete array of authentication and evaluation tools can be utilized to provide a well-rounded scientific approach to the authentication of botanical products. It is vital that the authenticity of botanical supplements be established using appropriate analysis tools regardless of whether the end products are being considered for evaluation in clinical studies or are being developed for the consumer market.

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