期刊
CLINICAL ORAL INVESTIGATIONS
卷 19, 期 1, 页码 77-83出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00784-014-1221-6
关键词
Lactobacillus rhamnosus GG; Bifidobacterium lactis BB-12; Probiotic; HOMIM; Mutans streptococci; Lactobacilli; Plaque index; Gingival index
资金
- TEKES, Finland
- Finnish Dental Society Apollonia
- Turku University Foundation
The aim was to evaluate the effects of orally administered Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp. lactis BB-12 (BB-12) on the number of salivary mutans streptococci (MS), amount of plaque, gingival inflammation and the oral microbiota in healthy young adults. The study was a randomised, controlled, double-blind trial. Healthy volunteers used lozenges containing a combination of LGG and BB-12 (test group, n = 29) or lozenges without added probiotics (control group, n = 31) for 4 weeks. At baseline and at the end of the test period, the plaque index (PI) and gingival index (GI) were determined, and stimulated saliva was collected. The microbial composition of saliva was assessed using human oral microbe identification microarray (n = 30). MS and lactobacilli (LB) were plate cultured. The probiotic lozenge decreased both PI and GI (p < 0.05) while no changes were observed in the control group. However, no probiotic-induced changes were found in the microbial compositions of saliva in either group. The probiotic lozenge improved the periodontal status without affecting the oral microbiota. Short-term consumption of LGG and BB-12 decreased the amount of plaque which was associated with a clinical impact: a decrease in gingival inflammation.
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