4.5 Article

Periodontal therapy and risk for adverse pregnancy outcomes

期刊

CLINICAL ORAL INVESTIGATIONS
卷 15, 期 5, 页码 609-615

出版社

SPRINGER HEIDELBERG
DOI: 10.1007/s00784-010-0424-8

关键词

Adverse pregnancy outcomes; Periodontal diseases/adverse effects; Periodontal diseases/therapy; Risk factors

资金

  1. Pontifical Catholic University of Minas Gerais [FIP2005-24-TLE1]

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Periodontitis has been associated with adverse pregnancy outcomes. Results from intervention studies are few and controversial. The present study assessed the effects of non-surgical periodontal treatment in the occurrence of adverse pregnancy outcomes. Two hundred forty-six eligible women were randomly divided into two groups: periodontitis intervention (n=122; undergoing non-surgical treatment during gestation) and periodontitis control (n=124; not treated during gestation). Univariate analysis was performed and estimates of relative risk were reported. Data from 225 women were analyzed. No differences for preterm birth (p=0.721), low birth weight (p=0.198), and preterm low birth weight (p=0.732) rates were observed. Relative risk estimates for preterm birth, low birth weight, and preterm low birth weight in the periodontitis intervention group were 0.915 (95% CI 0.561-1.493), 0.735 (95% CI 0.459-1.179), and 0.927 (0.601-1.431), respectively. Nonsurgical periodontal treatment during the second semester of gestation did not reduce the risk for preterm birth, low birth weight, and preterm low birth weight.

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