期刊
CLINICAL ORAL IMPLANTS RESEARCH
卷 23, 期 9, 页码 1082-1088出版社
WILEY
DOI: 10.1111/j.1600-0501.2011.02270.x
关键词
bone regeneration; bone substitutes; clinical research; clinical trials; guided tissue regeneration; sinus floor elevation
资金
- BioHorizons Inc.
- ICOI Implant Dentistry Research and Education Foundation Research Grant
- University of Michigan Periodontal Graduate Student Research Fund
Introduction Maxillary sinus augmentation is a predictable implant site development technique for posterior atrophic maxillary ridges. However, graft consolidation requires adequate angiogenesis and migration of osteogenic cells from native bone. Therefore, the amount of residual bone height (RBH) may play a role in the rate of graft maturation. The purpose of this study was to analyze the influence of RBH in the histomorphometric outcomes of maxillary sinus augmentation procedures. Material and methods Patients in need of sinus augmentation were recruited for the study. Customized radiographic guides were fabricated and a cone-beam computerized tomography scan was obtained at baseline. Two examiners measured RBH on the scans at the locations marked by the radiographic guide. Sinus grafting was performed by a lateral window approach using a particulated mineralized allograft. Patients were followed up for 6 similar to months. At the time of implant placement, bone core biopsies were harvested using the radiographic guide, which was converted into a surgical guide. Samples were histomorphometrically analyzed. Proportion of vital bone (%VB), remaining allograft particles (%RA), and non-mineralized tissue (%NMT) were quantified. Categorical analysis of correlation of RBH (<4 or =4 similar to mm) with%VB and%RA was performed using a statistical model. Results Twenty-one patients underwent sinus augmentation for a total of 21 sinuses. One patient developed an infection after grafting and was excluded. Histomorphometric analysis revealed that mean%VB was 20.47 similar to +/-similar to 18.25, mean %RA was 29.04 similar to +/-similar to 24.94, and average %NMT was 50.47 similar to +/-similar to 12.76. No significant correlation between RBH and %VB (r similar to=similar to 0.016; P similar to=similar to 0.951), and RBH and % (r similar to=similar to 0.009; P similar to=similar to 0.971) was found. Similarly, categorical analysis of correlation showed no statistical significance. Conclusion These findings suggest that the remaining alveolar bone height does not appear to influence the maturation and consolidation of an allograft in the maxillary sinus.
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