期刊
CLINICAL ONCOLOGY
卷 20, 期 7, 页码 548-554出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.clon.2008.04.018
关键词
chemotherapy; oncolytic virus; radiotherapy; reovirus
类别
Oncolytic viruses are tumour selective and able to lyse cancer cells after infection. Reovirus is an example of a wild-type oncolytic virus and is currently being investigated as a potential novel therapy for cancer. This overview gives a brief description of what is known about reovirus biology and summarises the preclinical data related to its oncolytic ability. The completed and ongoing clinical trials involving reovirus, both as a single agent and in combination with chemotherapy and radiotherapy, will be reviewed and their results discussed. Many of these clinical studies are being conducted by centres in the UK.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据