期刊
CLINICAL OBSTETRICS AND GYNECOLOGY
卷 56, 期 3, 页码 511-519出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0b013e31829cb9ca
关键词
fetal programming; maternal nutrition; placenta
There is a new developmental model for the origins of a wide range of chronic diseases. Under this model the causes to be identified are linked to normal variations in fetoplacental development. These variations are thought to lead to variations in the supply of nutrients to the baby that permanently alter gene expression, a process known as programming. According to the developmental model variations in the processes of development program the function of a few key systems that are linked to disease, including the immune system, antioxidant defenses, inflammatory responses, and the number and quality of stem cells.
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