期刊
CLINICAL OBSTETRICS AND GYNECOLOGY
卷 55, 期 1, 页码 3-23出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0b013e31824b4611
关键词
ovarian cancer; epidemiology; risk factors; etiology; pathogenesis
Little is known regarding the early aspects of ovarian carcinogenesis. As a consequence, the identification of women at risk for the disease is based primarily on clinical grounds, with family history being the most important risk factor. In this review, we will discuss the various hypotheses regarding ovarian etiology and pathogenesis. In addition, we will discuss the epidemiology of ovarian cancer, including hereditary, reproductive, hormonal, inflammatory, dietary, surgical, and geographic factors that influence ovarian cancer risk.
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