期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 55, 期 2, 页码 649-653出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201509124
关键词
aminations; click reactions; sulfenylation; triazoles
资金
- Natural Science Foundation of China
- Shandong province [21572118, JQ201505]
- subject construction funds of Shandong University [104.205.2.5, 2014JC008]
The 5-heterofunctionalized triazoles are important scaffolds in bioactive compounds, but current click reactions (CuAAC) cannot produce these core structures. A copper(I)-catalyzed interrupted click reaction to access diverse 5-functionalized triazoles is reported. Various 5-amino-, thio-, and selenotriazoles were readily assembled in one step in high yields. The reaction proceeds under mild conditions with complete regioselectivity. It also features a broad substrate scope and good functional group compatibility.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据