期刊
CLINICAL NUCLEAR MEDICINE
卷 43, 期 11, 页码 E419-E421出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000002280
关键词
positron emission tomography; glioblastoma multiforme; prostate-specific membrane antigen
资金
- Prostate Cancer Foundation Young Investigator Award
- National Institutes of Health [CA134675, CA184228, EB024495, CA183031]
Recent PET imaging of glioblastoma multiforme and other high-grade gliomas using prostate-specific membrane antigen (PSMA)-targeted small-molecule radiotracers suggests a role for these agents in diagnostic imaging of recurrent/residual tumor and that PSMA-targeted endoradiotherapies may provide a new approach to therapy for patients with these difficult-to-treat tumors. We present a case of cerebral radionecrosis demonstrating PSMA-targeted radiotracer uptake. Our findings may represent a potential pitfall and limitation to the diagnostic application of PSMA-targeted agents for high-grade gliomas.
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