期刊
CLINICAL NEUROLOGY AND NEUROSURGERY
卷 111, 期 6, 页码 523-526出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.clineuro.2009.02.005
关键词
Non-motor symptoms (NMSs); Non-Motor Symptoms Scale (NMSS); Parkinson's disease; Reliability; Validation
资金
- National Program of Basic Research of China [2006CB500706]
- National Natural Science Fund [30471918, 30570637]
- Program for Outstanding Medical Academic Leader [LJ 06003]
Objectives: To evaluate a Chinese version of the Non-Motor Symptoms Scale (NMSS) in Parkinson's disease (PD) as an instrument for measuring non-motor symptoms (NMSs) in Chinese patients with Parkinson's disease. Methods: We conducted a psychometric analysis of the Chinese version of NMSS using a cross-sectional study of 126 patients with PD. The battery also included the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), the Mini-Mental State Examination (MMSE), the Geriatric Depression Scale (GDS), and the Hamilton Anxiety Scale (HAMA), and was conducted by neurologists. Results: There were significant correlations between the NMSS and PSQI scores (rS=0.63, P < 0.001), as well as the NMSS and ESS scores (rS=0.38, P < 0.001). Furthermore, significant positive correlations between NMSS and GDS, NMSS and HAMA, and NMSS and disease duration were also observed. Importantly, the sleep/fatigue index of the NMSS significantly correlated with the PSQI and ESS findings, the mood/cognition index of the NMSS significantly correlated with the GDS and HAMA findings. and the attention/memory index of the NMSS significantly correlated with the MMSE findings. Conclusion:The Chinese version of the NMSS can be considered a comprehensive. useful measure for NMS evaluation in Chinese PD patients. (c) 2009 Elsevier B.V. All rights reserved.
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