期刊
CLINICAL NEUROLOGY AND NEUROSURGERY
卷 110, 期 4, 页码 396-399出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.clineuro.2007.12.009
关键词
schizencephaly; impulsivity; borderline personality; orbitofrontal cortex; cingulate cortex
Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly. (c) 2007 Elsevier B.V. All rights reserved.
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