期刊
CLINICAL MICROBIOLOGY AND INFECTION
卷 18, 期 1, 页码 54-60出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1469-0691.2011.03478.x
关键词
Bloodstream infection; carbapenem resistance; Klebsiella pneumoniae; outcome
The aim of this study was to evaluate the impact of carbapenem-resistant K. pneumoniae bloodstream infections on mortality. During the study period 42, 68 and 120 patients were identified with carbapenem-resistant, extended-spectrum beta-lactamase producers (ESBL) and susceptible K. pneumoniae bloodstream infections, respectively. Patients with carbapenem-resistant K. pneumoniae had higher rates of prior antimicrobial exposure, other nosocomial infections, and use of invasive devices. Infection-related mortality was 48% for carbapenem-resistant, 22% for ESBL producers and 17% for susceptible K. pneumoniae. Independent risk factors for infection-related mortality were Pitt bacteraemia score, Charlson score and carbapenem resistance.
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