期刊
CLINICAL MICROBIOLOGY AND INFECTION
卷 17, 期 3, 页码 404-408出版社
ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2010.03263.x
关键词
Astrovirus; epidemiology; gastroenteritis; genotype
资金
- National Institute of Health, Republic of Korea [NIH-091-4851-300]
P>The present study was conducted to survey the prevalence and genotypic distribution of human astrovirus (HAstV) circulating in South Korea. Of 160,027 patients with acute gastroenteritis, 2,057 (1.3%) were positive for HAstV antigen. We determined the genotypes of 187 HAstV strains collected from laboratories across the country. Genetic analysis revealed genotype 1 to be the most prevalent, accounting for 72.19% of the strains, followed by genotypes 8 (9.63%), 6 (6.95%), 4 (6.42%), 2 (3.21%) and 3 (1.60%). Our findings indicate that HAstV is less common but, even so, a potentially important viral agent of gastroenteritis in South Korea, with significant genetic diversity among circulating HAstV strains.
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