4.7 Article

An outbreak of norovirus infection in an Italian residential-care facility for the elderly

期刊

CLINICAL MICROBIOLOGY AND INFECTION
卷 15, 期 1, 页码 97-100

出版社

WILEY-BLACKWELL PUBLISHING, INC
DOI: 10.1111/j.1469-0691.2008.02117.x

关键词

Asymptomatic infection; norovirus outbreak; residential-care facility; sequence analysis; virus shedding

资金

  1. 'Ricerca Scientifica FIL [60A06-0979]
  2. University of Parma, Italy

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On December 2006, an outbreak of gastroenteritis occurred at a residential-care facility for the elderly in northern Italy. Thirty-five of 61 individuals interviewed (attack rate, 57.4%) fell ill. In 94.3% of cases, the onset of illness was within 48 h of a Christmas party at the facility. Norovirus (NoV) was detected by RT-PCR in 24 of 31 individuals examined, including three asymptomatic food-handlers, in whom there was evidence of long-lasting excretion of viral particles. The identification of a sequence referring to the '2006a GII. 4 NoV variant' in all examined strains supported the hypothesis of a common point source. This retrospective cohort study is the first report on an outbreak of NoV gastroenteritis in an Italian residential-care facility for the elderly.

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