期刊
CLINICAL MICROBIOLOGY AND INFECTION
卷 14, 期 4, 页码 391-393出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1469-0691.2007.01938.x
关键词
antigen kit; candidaemia; detection; mannanaemia; neonates; Platelia Candida assay
This preliminary study evaluated the use of the Platelia Candida antigen kit for the diagnosis of invasive candidosis in 70 of 184 pre-term infants admitted to a neonatal intensive care unit between March 2004 and March 2006. The frequency of confirmed candidaemia was 6.5%. The sensitivity and specificity of the assay were 94.4% and 94.2%, respectively, with a positive predictive value of 85% and a negative predictive value of 98%. These results suggest that the inclusion of regular serological surveillance for mannanaemia in some pre-term infants would complement blood cultures for the early detection of candidosis.
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