期刊
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
卷 10, 期 1, 页码 -出版社
CIG MEDIA GROUP, LP
DOI: 10.3816/CLML.2010.n.011
关键词
Autoimmune disorders; Diffuse large B-cell lymphoma; Immunomodulators; Lymphoproliferative disorders; Psoriasis
Lymphomas have been associated with immunodeficiency disorders, including those acquired secondary to the use of immunosuppressants for autoimmune disorders and for the prevention of graft rejection. Biologic agents have also been associated with the development of lymphoproliferative disorders. We report the case of Epstein-Barr Virus-negative diffuse large B-cell lymphoma associated with efalizumab, a monoclonal antibody that inhibits T-cell activity. Discontinuation of efalizumab resulted in a partial remission of lymphoma, although administration of chemotherapy was ultimately required. The use of immunomodulators must be tempered with the knowledge of their effect on the immune system and their association with lymphoproliferative disorders.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据