期刊
CLINICAL LIPIDOLOGY
卷 6, 期 1, 页码 79-91出版社
FUTURE MEDICINE LTD
DOI: 10.2217/CLP.10.89
关键词
cardiovascular; epidemiology; imaging; mechanisms; perivascular adipose tissue
资金
- Intramural NIH HHS [Z99 HL999999, ZIA HL006094-01] Funding Source: Medline
Perivascular adipose tissue is a local deposit of adipose tissue surrounding the vasculature. Perivascular adipose tissue is present throughout the body and has been shown to have a local effect on blood vessels. The influence of perivascular adipose tissue on the vasculature changes with increasing adiposity. This article describes the anatomy and pathophysiology of perivascular adipose tissue and the experimental evidence supporting its local adverse effect on the vasculature. Methods for quantifying perivascular adipose tissue in free-living populations will be described. Finally, the epidemiological literature demonstrating an association between perivascular adipose tissue and cardiometabolic disease will be explored.
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