期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 54, 期 48, 页码 14442-14446出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201507918
关键词
chirality; macrocycles; peptides; self-assembly; supramolecular chemistry
资金
- Japan Society for the Promotion of Science (JSPS) [25220804, 26810047]
- Nanotechnology Platform Program (Molecule and Material Synthesis) of the Ministry of Education, Culture, Sports, Science and Technology, Japan
- Grants-in-Aid for Scientific Research [26810047] Funding Source: KAKEN
The dynamic planar chirality in a peptide-bound Ni-II-salphen-based macrocycle can be remotely controlled. First, a right-handed (P)-3(10)-helix is induced in the dynamic helical oligopeptides by a chiral amino acid residue far from the macrocyclic framework. The induced planar chirality remains dynamic in chloroform and acetonitrile, but is almost completely locked in fluoroalcohols as a result of the solvent-induced transition of the peptide chains from a 3(10)-helix to a wider a-helix, which freezes the rotation of the pendant peptide units around the macrocycle.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据