期刊
CLINICAL INFECTIOUS DISEASES
卷 50, 期 7, 页码 1006-1010出版社
UNIV CHICAGO PRESS
DOI: 10.1086/651077
关键词
-
资金
- Ugandan Ministry of Health
- World Health Organization
- UNICEF
- United Nations High Commission for Refugees
- Medecins sans Frontiers
- St. Joseph Hospital
- Kitgum Hospital
- Madi Opei Level 4 Health Center
- Centers for Disease Control and Prevention in Uganda
Background. Outbreaks of infection with hepatitis E virus (HEV) are frequently attributed to contaminated drinking water, even if direct evidence for this is lacking. Methods. We conducted several epidemiologic investigations during a large HEV infection outbreak in Uganda. Results. Of 10,535 residents, 3218 had HEV infection; of these, 2531 lived in households with > 1 case. HEV was not detected in drinking water or zoonotic sources. Twenty-five percent of cases occurred >= 8 weeks after onset of hepatitis in an index case in the household. Households with >= 2 cases were more likely to have a member(s) who attended a funeral, had close contact with a jaundiced person, or washed hands in a common basin with others (P < .05 for all). Conclusions. A high attack rate in households, lack of a common source of infection, and poor hygienic practices in households with >= 2 cases suggest person-to-person transmission of HEV during this outbreak.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据