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Pandemic Influenza A (H1N1) Outbreak among 15 School-Aged HIV-1-Infected Children

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CLINICAL INFECTIOUS DISEASES
卷 51, 期 11, 页码 E90-E94

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OXFORD UNIV PRESS INC
DOI: 10.1086/657121

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Patients infected with human immunodeficiency virus type 1 (HIV-1) are considered to be at increased risk for 2009 H1N1 influenza-related complications. We performed an observational study after an outbreak of 2009 H1N1 influenza virus infection among a group of 15 HIV-1-infected school-aged children in Germany in October 2009. Clinical course, kinetics of viral shedding, and antibody response among children with CD4 cell counts >350 cells/mu L and 2009 H1N1 influenza virus coinfection did not appear to differ from that among healthy children. Oseltamivir shortened the duration of viral shedding.

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