期刊
CLINICAL INFECTIOUS DISEASES
卷 47, 期 10, 页码 1321-1327出版社
OXFORD UNIV PRESS INC
DOI: 10.1086/592690
关键词
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资金
- National Institute of Health/National Institute of Allergy and Infectious Diseases [R01 AI 054719-01]
- Public Health Science [AI 73896, AI 28388]
Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Disease presentation and outcomes may be affected by, among other factors, the use of calcineurin inhibitor immunosuppressive agents. It is being increasingly recognized that rapid reversal of immunosuppression in transplant recipients treated for cryptococcosis incurs the risk of immune reconstitution inflammatory syndrome, which resembles worsening disease or relapse. This review summarizes the current state of knowledge regarding cryptococcosis in transplant recipients and highlights areas where future investigations are needed to further optimize outcomes for these patients.
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