相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: Implications for human motor neuron disease
Ralf Palmisano et al.
BMC NEUROSCIENCE (2011)
Rab7: Role of its protein interaction cascades in endo-lysosomal traffic
Tuanlao Wang et al.
CELLULAR SIGNALLING (2011)
Transformation of Rat Intestinal Epithelial Cells by Overexpression of Rab25 is Microtubule Dependent
Lynne A. Lapierre et al.
CYTOSKELETON (2011)
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1
Xiaomin Hou et al.
EMBO JOURNAL (2011)
Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation
Asako Otomo et al.
FEBS LETTERS (2011)
Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy
Edgar A. Otto et al.
JOURNAL OF MEDICAL GENETICS (2011)
Role of Rab GTPases in Membrane Traffic and Cell Physiology
Alex H. Hutagalung et al.
PHYSIOLOGICAL REVIEWS (2011)
A novel statin-mediated prenylation block-and-release assay provides insight into the membrane targeting mechanisms of small GTPases
Bassam R. Ali et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant
Ananthamurthy Nagabhushana et al.
BMC CELL BIOLOGY (2010)
The RIN2 syndrome: a new autosomal recessive connective tissue disorder caused by deficiency of Ras and Rab interactor 2 (RIN2)
Delfien Syx et al.
HUMAN GENETICS (2010)
Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation
Brett A. McCray et al.
HUMAN MOLECULAR GENETICS (2010)
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas
Ki Taek Nam et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Structure-Based Design and Synthesis of Potent, Ethylenediamine-Based, Mammalian Farnesyltransferase Inhibitors as Anticancer Agents
Steven Fletcher et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
The Mood Stabilizer Valproic Acid Improves Defective Neurite Formation Caused by Charcot-Marie-Tooth Disease-Associated Mutant Rab7 Through the JNK Signaling Pathway
Junji Yamauchi et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
ADP-Ribosylation Factors Modulate the Cell Surface Transport of G Protein-Coupled Receptors
Chunmin Dong et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Rubicon and PLEKHM1 Negatively Regulate the Endocytic/Autophagic Pathway via a Novel Rab7-binding Domain
Keisuke Tabata et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Rab7 Mutants Associated with Charcot-Marie-Tooth Disease Exhibit Enhanced NGF-Stimulated Signaling
Soumik BasuRay et al.
PLOS ONE (2010)
LG186: An Inhibitor of GBF1 Function that Causes Golgi Disassembly in Human and Canine Cells
Frederic Boal et al.
TRAFFIC (2010)
Identification of a Small GTPase Inhibitor Using a High-Throughput Flow Cytometry Bead-Based Multiplex Assay
Zurab Surviladze et al.
JOURNAL OF BIOMOLECULAR SCREENING (2010)
RIN2 Deficiency Results in Macrocephaly, Alopecia, Cutis Laxa, and Scoliosis: MACS Syndrome
Lina Basel-Vanagaite et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2009)
Cyclodextrins promote protein aggregation posing risks for therapeutic applications
Min S. Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Great Expectations for PIP: Phosphoinositides as Regulators of Signaling During Development and Disease
Lara C. Skwarek et al.
DEVELOPMENTAL CELL (2009)
Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration
Phillip A. Vanlandingham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Endosomal Adaptor Proteins APPL1 and APPL2 Are Novel Activators of β-Catenin/TCF-mediated Transcription
Sajid Rashid et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity
Salit Tzaban et al.
JOURNAL OF CELL BIOLOGY (2009)
Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity
Xueyi Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Mutant Huntingtin Impairs Post-Golgi Trafficking to Lysosomes by Delocalizing Optineurin/Rab8 Complex from the Golgi Apparatus
Daniel del Toro et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies
Stephanie L. Bielas et al.
NATURE GENETICS (2009)
The Emerging Role of the RAB25 Small GTPase in Cancer
Roshan Agarwal et al.
TRAFFIC (2009)
Regulation of endosomal motility and degradation by amyotrophic lateral sclerosis 2/alsin
Chen Lai et al.
MOLECULAR BRAIN (2009)
Disorders of Lysosome-Related Organelle Biogenesis: Clinical and Molecular Genetics
Marjan Huizing et al.
Annual Review of Genomics and Human Genetics (2008)
Rab GTPases and their roles in brain neurons and glia
Ee Ling Ng et al.
BRAIN RESEARCH REVIEWS (2008)
Large ARF guanine nucleotide exchange factors in membrane trafficking
N. Anders et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Characterization of pip5k3 fleck corneal dystrophy-linked gene in zebrafish
Gaelle Boisset et al.
GENE EXPRESSION PATTERNS (2008)
Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking
Canhong Cao et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Loss of the Batten Disease Gene CLN3 Prevents Exit from the TGN of the Mannose 6-Phosphate Receptor
Daniel J. Metcalf et al.
TRAFFIC (2008)
Rab25 associates with α5β1 integrin to promote invasive migration in 3D microenvironments
Patrick T. Caswell et al.
DEVELOPMENTAL CELL (2007)
Involvement of Rabring7 in EGF receptor degradation as an E3 ligase
Ayuko Sakane et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
Maxence V. Nachury et al.
CELL (2007)
Rin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradation
Chen Kong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans
Liesbeth Van Wesenbeeck et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest
George B. Kyei et al.
EMBO JOURNAL (2006)
Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of β1-integrins
Teijo Pellinen et al.
JOURNAL OF CELL BIOLOGY (2006)
Structure-function based design of small molecule inhibitors targeting Rho family GTPases
Nicolas Nassar et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
TBC domain family, member 15 is a novel mammalian Rab GTPase-activating protein with substrate preference for Rab7
XM Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Alsin is partially associated with centrosome in human cells
S Millecamps et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)
Structural basis of family-wide Rab GTPase recognition by rabenosyn-5
S Eathiraj et al.
NATURE (2005)
Rab14 is involved in membrane trafficking between the Golgi complex and endosomes
JR Junutula et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer
MNJ Seaman
JOURNAL OF CELL BIOLOGY (2004)
Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
YL Hao et al.
JOURNAL OF NEUROSCIENCE (2004)
Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway
K Luiro et al.
HUMAN MOLECULAR GENETICS (2004)
Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor
JD Topp et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Targeting RAB GTPases to distinct membrane compartments
S Pfeffer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers
KW Cheng et al.
NATURE MEDICINE (2004)
Rab7 is required for the normal progression of the autophagic pathway in mammalian cells
MG Gutierrez et al.
JOURNAL OF CELL SCIENCE (2004)
Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy
K Verhoeven et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
Human VPS34 and p150 are rab7 interacting partners
MP Stein et al.
TRAFFIC (2003)
Characterization of the in vitro retrograde transport of MPR46
GR Medigeshi et al.
TRAFFIC (2003)
Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre
L Martinu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Modulation of cellular cholesterol transport and homeostasis by Rab11
M Hölttä-Vuori et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
rab4 regulates transport to the apical plasma membrane in Madin-Darby canine kidney cells
K Mohrmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Rab GTPases: specifying and deciphering organelle identity and function
SR Pfeffer
TRENDS IN CELL BIOLOGY (2001)
Identification and characterization of a family of Rab11-interacting proteins
CM Hales et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking
P Burke et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Role of Rab9 GTPase in facilitating receptor recruitment by TIP47
KS Carroll et al.
SCIENCE (2001)
The cellular neurobiology of depression
HK Manji et al.
NATURE MEDICINE (2001)
Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes
G Cantalupo et al.
EMBO JOURNAL (2001)
Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: Lessons from mechanism and bench-to-bedside translational studies
SM Sebti et al.
ONCOGENE (2000)
The mammalian Rab family of small GTPases: Definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily
JB Pereira-Leal et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)