期刊
CLINICAL EEG AND NEUROSCIENCE
卷 41, 期 2, 页码 61-67出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/155005941004100204
关键词
Basal Ganglia; Circuit Disorder; Dopamine; Pallidum; Parkinson's Disease; Pathophysiology; Striatum; Subthalamic Nucleus
资金
- NCRR NIH HHS [P51 RR000165] Funding Source: Medline
- NINDS NIH HHS [R01 NS054976, P50 NS071669] Funding Source: Medline
The basal ganglia (BG) have long been considered to play an important role in the control of movement and the pathophysiology of movement disorders, such as Parkinson's disease (PD). Studies over the past decades have considerably broadened this view, indicating that the BG participate in multiple, parallel, largely segregated, cortico-subcortical reentrant pathways involving motor, associative and limbic functions. Research has shown that dysfunction within individual circuits is associated not only with movement disorders, but also with neuropsychiatric disorders. Accordingly, a number of movement disorders and neuropsychiatric disorders such as obsessive compulsive disorder and burette's syndrome are viewed as circuit disorders. We here discuss the changes in our current understanding of the anatomic and functional organization of BC circuits and related circuit disorders.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据