期刊
CLINICAL CANCER RESEARCH
卷 17, 期 19, 页码 6130-6139出版社
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-11-0659
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资金
- NIH [T32 CA-009666, CA-136980]
- National Research Service Award (NRSA) Research Training Grant
- Conquer Cancer Foundation
- NIH/National Cancer Institute (NCI) [CA-106672]
Fibroblast growth factor (FGF) signaling regulates cell proliferation, differentiation, survival, angiogenesis, and wound healing. Compelling evidence for deregulated FGF signaling in tumorigenesis continues to emerge, and a growing body of research suggests that FGF may also play an integral role in the resistance to anti-VEGF therapy. Although agents targeting FGF signaling are early in development, the potential to target both the VEGF and FGF pathways may translate into improvements in the clinical care of cancer patients. Clin Cancer Res; 17(19); 6130-9. (C) 2011 AACR.
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