期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 54, 期 23, 页码 6809-6813出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201501617
关键词
cross-coupling; density functional theory calculations; palladium; reaction mechanisms; synthetic methods
资金
- RWTH Aachen University
- MIWF NRW
- RWTH Bull Cluster in Aachen [JARA0091]
While palladium catalysis is ubiquitous in modern chemical research, the recovery of the active transition-metal complex under routine laboratory applications is frequently challenging. Described herein is the concept of alternative cross-coupling cycles with a more robust (air-, moisture-, and thermally-stable) dinuclear Pd-I complex, thus avoiding the handling of sensitive Pd-0 species or ligands. Highly efficient CSCF3 coupling of a range of aryl iodides and bromides was achieved, and the recovery of the Pd-I complex was accomplished via simple open-atmosphere column chromatography. Kinetic and computational data support the feasibility of dinuclear Pd-I catalysis. A novel SCF3-bridged Pd-I dimer was isolated, characterized by X-ray crystallography, and verified to be a competent catalytic intermediate.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据