期刊
CLINICAL AUTONOMIC RESEARCH
卷 28, 期 6, 页码 509-518出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s10286-018-0560-9
关键词
Autonomic nervous system; Breathing; Sleep; Sympathetic; Parasympathetic
资金
- National Institute for Nursing Research [R00NR014369]
- NATIONAL INSTITUTE OF NURSING RESEARCH [R00NR014369] Funding Source: NIH RePORTER
Cardiovascular and respiratory parameters change during sleep and wakefulness. This observation underscores an important, albeit incompletely understood, role for the central nervous system in the differential regulation of autonomic functions. Understanding sleep/wake-dependent sympathetic modulations provides insights into diseases involving autonomic dysfunction. The purpose of this review was to define the central nervous system nuclei regulating sleep and cardiovascular function and to identify reciprocal networks that may underlie autonomic symptoms of disorders such as insomnia, sleep apnea, restless leg syndrome, rapid eye movement sleep behavior disorder, and narcolepsy/cataplexy. In this review, we examine the functional and anatomical significance of hypothalamic, pontine, and medullary networks on sleep, cardiovascular function, and breathing.
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