3.9 Article

Seroepidemiology of Astrovirus MLB1

期刊

CLINICAL AND VACCINE IMMUNOLOGY
卷 21, 期 6, 页码 908-911

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AMER SOC MICROBIOLOGY
DOI: 10.1128/CVI.00100-14

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资金

  1. National Institutes of Health/National Center for Research Resources Washington University-ICTS [KL2 RR024994]
  2. National Institutes of Health [R21 AI090199]
  3. Children's Discovery Institute [MD-FR-2013-292]
  4. Biomedical Foundation
  5. ALSAC

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To determine the seroprevalence of astrovirus MLB1 (MLB1), an indirect enzyme-linked immunosorbent assay (ELISA) was established. MLB1 seropositivity was high in children <6 months old, decreased to a nadir at 12 to 23 months old, and increased to 100% by adulthood. MLB1 infection is common, and primary exposure occurs in childhood.

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